Measurement of AGEs
Advanced glycation end-products (AGEs) are a complex group of molecules that have been found almost everywhere among tissues and organs of the human body.
The pool of AGEs in the human body can have two origins:
• endogenous - by the production of the body itself during the normal ageing process.
• exogenous – by eating heat-treated food, which are rich in AGEs.
Their concentration increases with age and is also related to different diseases and pathological conditions:
• Cardiovascular diseases
• Alzheimer’s disease
• Anemia
• Sarcopenia
• Osteoporosis
• Chronic kidney disease and renal failure
• Cataract and macular degeneration
Due to its effects on ageing and human health, and since food is a major source, several analytical techniques have been used to measure the content of AGEs in food.
Institut Kurz is the first laboratory to develop these methods.
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